IS Case 237: Ollier's disease

Mary Fontanella, MD

Imaging Sciences URMC 2008
Publication Date: 2009-05-26


Patient is a 33-year-old male with Ollier's disease having Increasing right extremity pain over the past year.


Images from whole-body bone scan demonstrate multiple areas of increased radiotracer uptake in the bilateral scapulae, femurs, right humerus, and most intense in the right ilium, femur and tibia. Plain films in corresponding areas to those of increased radiotracer uptake demonstrate enchondromas with deformity of the right hemipelvis, femur, tibia and fibula.


Ollier's disease


Ollier's disease is a condition of multiple enchondromas, first manifesting in the first decade of life. Prevalence is 1/100,000. Distribution of the enchondromas is variable and complications can include skeletal deformities, limb length discrepancy, and variably malignant degeneration to chondrosarcoma in 5-50% of cases.

Differential diagnosis includes Maffucci syndrome, with the distinguishing characteristic being the presence of hemangiomas in Maffucci Syndrome.


  1. Silve C, Jüppner H. Ollier disease. Orphanet J Rare Dis. 2006 Sep 22;1:37. [PMID: 16995932]

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