IS Case 273: Treated lymphoma
Imaging Sciences URMC 2009
Publication Date: 2009-07-29
Calcified lymph nodes in the mediastinum can have a variety of etiologies. They can be seen with infection such as tuberculosis, histoplasmosis, or coccidioidomycosis; pneumoconioses such as silicosis or coal worker's pneumoconiosis; inflammatory diseases such as sarcoidosis; and cases of treated lymphoma. Differentiation can often be made with appropriate clinical history, physical exam, and laboratory findings.
This case demonstrates diffuse, dense calcifications in the anterior mediastinum in a patient with history of lymphoma. Treated lymphoma can have egg shell type or irregular calcifications or diffuse calcifications. The calcified lymph nodes can be larger than typically seen with granulomatous disease. Calcification of lymph nodes in patients with untreated lymphoma are very rare.
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