IS Case 364: Grade IV intracranial hemorrhage
2009 URMC Imaging Sciences
Publication Date: 2010-03-02
Patient is a 9-day-old 24 weeks pre-term infant on an oscillator.
Germinal matrix hemorrhage occurs in the germinal zone, a highly vascular region in the caudothalamic groove that is extremely sensitive to oxygenation changes. Most germinal matrix hemorrhages occur in the first week of life. It is related to perinatal stress such as labile blood pressure, hypoxia and hypercarbia, etc. It is most commonly seen in infants < 32 weeks gestation and weighing less than 1000 grams.
I - Confined to caudothalamic groove
II - Extends into the ventricle but does not expand it
IV - Parenchymal hemorrhage
* Secondary hydrocephalus may occur
- Leung A, Islam O. Germinal matrix hemorrhage. Emedicine. December 22, 2008. http://emedicine.medscape.com/article/408862-overview
- Donnelly LF. Germinal matrix hemorrhage. IN: Fundamentals of Pediatric Radiology. Saunders. 2001; 223-224.