IS Case 435: Phthisis bulbi

Jeremy Sykes, MD

University of Rochester

Imaging Sciences URMC 2010
Publication Date: 2010-08-27


Patient is a 44-year-old male with vertigo and left-sided weakness.


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Phthisis bulbi


Phthisis bulbi refers to a calcified, shrunken non-functioning globe. This abnormality of the globe indicates end-stage change from a number of possible causes. These may include post-infectious, post-inflammatory, post-traumatic, or post-surgical etiologies. Severe ocular disease such as untreated retinal detachment may also lead to phthisis bulbi. Calcification or ossification usually begins in the posterior pole of the globe and progresses anteriorly toward the ciliary body. CT features include a small and often disorganized globe with partial or complete calcification of the rim. It is an incidental finding and reflects a chronic process.


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