IS Case 592: Thrombus formation in the IVC from hypercoagulable state leading to pulmonary embolism
Imaging Sciences URMC 2010
Publication Date: 2011-11-17
CT images of the abdomen revealed a large inferior vena cava (IVC) thrombus. Chest CT images revealed a right middle lobe segmental pulmonary embolism (PE) with a peripheral wedge shaped lung infarction.
This is an excellent example of how a hypercoagulable state such as malignancy can lead to thrombus formation in the venous circulation and then to pulmonary embolism as small thrombi are taken off of the main thrombus due to flow and carried into the pulmonary vasculature. Other risk factors for pulmonary embolism include postoperative patient, trauma and burn, prior history for PE or DVT, immobility, obesity, CHF, neurologic event, hormonal events, coagulopathies.
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